A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements
© 2019 Bhagavathi Sundaram Sivamaruthi et al. Probiotics are now recognized for several health benefits and they have been recommended as a complementary therapeutic agent for metabolic disorders. Obesity is an altered health condition, which is a resultant of irregular energy intake and energy bala...
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th-cmuir.6653943832-654092019-08-05T04:38:21Z A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements Bhagavathi Sundaram Sivamaruthi Periyanaina Kesika Natarajan Suganthy Chaiyavat Chaiyasut Biochemistry, Genetics and Molecular Biology Immunology and Microbiology © 2019 Bhagavathi Sundaram Sivamaruthi et al. Probiotics are now recognized for several health benefits and they have been recommended as a complementary therapeutic agent for metabolic disorders. Obesity is an altered health condition, which is a resultant of irregular energy intake and energy balance, changes in gut microbiota, and improper diet with the influence of genetic makeup and environmental factors. Several studies revealed the influence of probiotic supplementation on obesity-associated consequences in vitro, in vivo, and in human clinical studies. The current manuscript discussed the factors influencing the occurrence of obesity, the interplay between microbiome and obesity, the effect of the probiotic intervention on the health status of obese people, and possible mechanism of antiobesity activity of probiotics. The literature survey revealed that the antiobese activity of probiotics might be associated with their ability to alter the intestinal microbiota, remodeling of energy metabolism, alter the expression of genes related to thermogenesis, glucose metabolism, and lipid metabolism, and change the parasympathetic nerve activity. Further intense research is necessary to figure out the best probiotic or synbiotic mixture and optimum dosage and duration of the intervention to reduce obesity and prevent the recurring of obese condition. 2019-08-05T04:32:58Z 2019-08-05T04:32:58Z 2019-01-01 Journal 23146141 23146133 2-s2.0-85066019293 10.1155/2019/3291367 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066019293&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/65409 |
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Biochemistry, Genetics and Molecular Biology Immunology and Microbiology Bhagavathi Sundaram Sivamaruthi Periyanaina Kesika Natarajan Suganthy Chaiyavat Chaiyasut A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements |
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© 2019 Bhagavathi Sundaram Sivamaruthi et al. Probiotics are now recognized for several health benefits and they have been recommended as a complementary therapeutic agent for metabolic disorders. Obesity is an altered health condition, which is a resultant of irregular energy intake and energy balance, changes in gut microbiota, and improper diet with the influence of genetic makeup and environmental factors. Several studies revealed the influence of probiotic supplementation on obesity-associated consequences in vitro, in vivo, and in human clinical studies. The current manuscript discussed the factors influencing the occurrence of obesity, the interplay between microbiome and obesity, the effect of the probiotic intervention on the health status of obese people, and possible mechanism of antiobesity activity of probiotics. The literature survey revealed that the antiobese activity of probiotics might be associated with their ability to alter the intestinal microbiota, remodeling of energy metabolism, alter the expression of genes related to thermogenesis, glucose metabolism, and lipid metabolism, and change the parasympathetic nerve activity. Further intense research is necessary to figure out the best probiotic or synbiotic mixture and optimum dosage and duration of the intervention to reduce obesity and prevent the recurring of obese condition. |
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Journal |
author |
Bhagavathi Sundaram Sivamaruthi Periyanaina Kesika Natarajan Suganthy Chaiyavat Chaiyasut |
author_facet |
Bhagavathi Sundaram Sivamaruthi Periyanaina Kesika Natarajan Suganthy Chaiyavat Chaiyasut |
author_sort |
Bhagavathi Sundaram Sivamaruthi |
title |
A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements |
title_short |
A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements |
title_full |
A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements |
title_fullStr |
A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements |
title_full_unstemmed |
A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements |
title_sort |
review on role of microbiome in obesity and antiobesity properties of probiotic supplements |
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2019 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066019293&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/65409 |
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