One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline

One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline

The one-pot three-components synthesis of 3-(α-arylaminobenzyl)indoles is achieved from indole, aromatic aldehydes and anilines by using L-proline as a catalyst. The reaction produced 3-alkyl-indoles in dominance over the bisindolyl alkanes. The reported L-proline catalyzed synthetic methodology is...

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Main Authors: Tahira Naqvi, Masood Ahmad Rizvi, Kamal K. Kapoor
Language:English
Published: Science Faculty of Chiang Mai University 2019
Subjects:
Organocatalysis
one-pot synthesis
multi-component reaction
Online Access:http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=6242
http://cmuir.cmu.ac.th/jspui/handle/6653943832/66154
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-661542019-08-21T09:18:22Z One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline Tahira Naqvi Masood Ahmad Rizvi Kamal K. Kapoor Organocatalysis one-pot synthesis multi-component reaction The one-pot three-components synthesis of 3-(α-arylaminobenzyl)indoles is achieved from indole, aromatic aldehydes and anilines by using L-proline as a catalyst. The reaction produced 3-alkyl-indoles in dominance over the bisindolyl alkanes. The reported L-proline catalyzed synthetic methodology is an environmentally benign alternative for the synthesis of 3-alkyl-indoles with comparable catalytic efficiency to that of costly and toxic metal based catalysts. 2019-08-21T09:18:22Z 2019-08-21T09:18:22Z 2015 Chiang Mai Journal of Science 42, 4 (Oct 2015), 877 - 885 0125-2526 http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=6242 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66154 Eng Science Faculty of Chiang Mai University
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
topic Organocatalysis
one-pot synthesis
multi-component reaction
spellingShingle Organocatalysis
one-pot synthesis
multi-component reaction
Tahira Naqvi
Masood Ahmad Rizvi
Kamal K. Kapoor
One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline
description The one-pot three-components synthesis of 3-(α-arylaminobenzyl)indoles is achieved from indole, aromatic aldehydes and anilines by using L-proline as a catalyst. The reaction produced 3-alkyl-indoles in dominance over the bisindolyl alkanes. The reported L-proline catalyzed synthetic methodology is an environmentally benign alternative for the synthesis of 3-alkyl-indoles with comparable catalytic efficiency to that of costly and toxic metal based catalysts.
author Tahira Naqvi
Masood Ahmad Rizvi
Kamal K. Kapoor
author_facet Tahira Naqvi
Masood Ahmad Rizvi
Kamal K. Kapoor
author_sort Tahira Naqvi
title One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline
title_short One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline
title_full One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline
title_fullStr One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline
title_full_unstemmed One-pot Three Components Synthesis of 3-(α-arylaminobenzylidene)indoles Catalysed by L-proline
title_sort one-pot three components synthesis of 3-(α-arylaminobenzylidene)indoles catalysed by l-proline
publisher Science Faculty of Chiang Mai University
publishDate 2019
url http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=6242
http://cmuir.cmu.ac.th/jspui/handle/6653943832/66154
_version_ 1681426402083078144

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