Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage
Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Ma...
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Faculty of Medicine, Chiang Mai University
2019
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| 在線閱讀: | https://www.tci-thaijo.org/index.php/CMMJ-MedCMJ/article/view/144446 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66329 |
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th-cmuir.6653943832-663292019-08-21T09:18:26Z Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage ความสัมพันธ์ระหว่างระดับคอเลสเตอรอลในเลือดต่ำกับการเพิ่มความเสี่ยงภาวะเลือดออกในสมอง Kriangsak Champawong Chumpon Jetjumnong risk factors primary intracerebral hemorrhage Thai cholesterol Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Mar, Jun, Sep, and Dec). Objective Several of the risk factors that increase the risk of primary intracerebral hemorrhage (PICH) are well documented. However, the association between serum cholesterol levels and PICH is still controversial. The objective of this study was to evaluate the correlation between serum cholesterol levels and PICH in Thai people. Methods In this retrospective case-control study, the serum cholesterol levels in PICH patients were compared to an independent control group in a primary care practice hospital in patients having yearly health check ups during the study. Participants were matched for age, gender, and race. The lowest quartile of the pooled blood lipid distribution was designated as the low cholesterol threshold. Results From 2015 to 2016, 55 cases of PICH and 112 control cases were enrolled. The mean total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) level in the PICH group was signi fi cantly lower than the control group (TC 176 mg/dL vs 211 mg/dL, p<0.001; LDL-C 107.2 mg/dL vs 145 mg/dL, p<0.001, respectively). A low LDL-C also increases the odds of hemorrhage by 11.78-fold (3.78-36.67, p< 0.001) after adjustment for covariates. Conclusions Low serum TC and LDL-C levels are associated with an increased risk of PICH in Thai people. 2019-08-21T09:18:26Z 2019-08-21T09:18:26Z 2019 Chiang Mai Medical Journal 57, 4 (Oct-Dec 2019), 165-171 0125-5983 https://www.tci-thaijo.org/index.php/CMMJ-MedCMJ/article/view/144446 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66329 Eng Faculty of Medicine, Chiang Mai University |
| institution |
Chiang Mai University |
| building |
Chiang Mai University Library |
| country |
Thailand |
| collection |
CMU Intellectual Repository |
| language |
English |
| topic |
risk factors primary intracerebral hemorrhage Thai cholesterol |
| spellingShingle |
risk factors primary intracerebral hemorrhage Thai cholesterol Kriangsak Champawong Chumpon Jetjumnong Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| description |
Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Mar, Jun, Sep, and Dec). |
| author |
Kriangsak Champawong Chumpon Jetjumnong |
| author_facet |
Kriangsak Champawong Chumpon Jetjumnong |
| author_sort |
Kriangsak Champawong |
| title |
Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| title_short |
Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| title_full |
Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| title_fullStr |
Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| title_full_unstemmed |
Association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| title_sort |
association of low serum cholesterol levels with increased risk of primary intracerebral hemorrhage |
| publisher |
Faculty of Medicine, Chiang Mai University |
| publishDate |
2019 |
| url |
https://www.tci-thaijo.org/index.php/CMMJ-MedCMJ/article/view/144446 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66329 |
| _version_ |
1681426434399141888 |