Statistical Optimization for the Production of D-Mannose Isomerase by Saccharothrix sp. CMU-K747 Using Response Surface Methodology

• Main Authors: ApiradeeSiangsuepchart", SaisamornLumyong
• Language: English
• Published: Science Faculty of Chiang Mai University 2019
• Subjects: Response surface methodology; Medium optimization; D-Mannose isomerase production; Central composite design; Saccharothrixsp. CMU-K747
• Online Access: http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=5513; http://cmuir.cmu.ac.th/jspui/handle/6653943832/66825
• Institution: Chiang Mai University

Response surface methodology (RSM) and central composite design (CCD) were employed to find the optimal fermentation medium for producing intracellular D-mannose isomerase (D-MI) using Saccharothrix sp. CMU-K747. The two variables involved in this study were D-mannose and soybean meal. The statistic...