A novel gelatin crosslinking method retards release of mulberry 1-deoxynojirimycin providing a prolonged hypoglycaemic effect

• المؤلفون الرئيسيون: Vichasilp C., Nakagawa K., Sookwong P., Higuchi O., Kimura F., Miyazawa T.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-84861573909&partnerID=40&md5=695d15649a4e75bb64b5d40c5304885d; http://cmuir.cmu.ac.th/handle/6653943832/6701
• المؤسسة: Chiang Mai University

Mulberry 1-deoxynojirimycin (DNJ), a potent α-glycosidase inhibitor, has therapeutic potency in the suppression of postprandial blood glucose levels thereby possibly preventing diabetes mellitus. However, DNJ has a relatively short half-life in vivo (about 2 h). Therefore, several doses of mulberry...