Synthesis of racemic and optically active forms of novel antimalarial agents, spirocyclopentanone-anthracene adducts, via tandem Michael addition-Dieckmann condensation reactions as the key steps

• Main Authors: Choommongkol R., Jongkol R., Prabpai S., Kongsaeree P., Meepowpan P.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84860307253&partnerID=40&md5=514b8ff225a777e81d8328f6ceb56e40; http://cmuir.cmu.ac.th/handle/6653943832/6706
• Institution: Chiang Mai University

Spirocyclopentanone-anthracene adducts, novel antimalarial agents, have been synthesized by employing the racemic and the optically active dimethyl itaconate-anthracene adducts in a reaction with piperine via tandem Michael addition-Dieckmann condensation reactions as the key steps. All adducts exhi...