The in-house monoclonal antibody against γ-globin chain; Thal N/B, accurately measured F cells in SEA-α thalassemia 1 trait

• Main Authors: Lamplaimas Tangpan, Tippawadee Jansai, Sasiwan Kerdpoo, Tiemjan Kiewkarnkha, Ekthong Limweeraprajak, Thanusak Tatu
• Format: Journal
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Health Professions; Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85073934815&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/67605
• Institution: Chiang Mai University

© 2019, © 2019 Taylor & Francis. The monoclonal antibody (mAb) against γ-globin chain clone Thal N/B was produced. It was aimed at measuring the quantity of HbF (α2γ2)-containing red blood cells or F cells by flow cytometry. However, it may cross-react with Hb Bart’s (γ4) which is present in t...