Antibacterial and cytotoxic activities of phenolic constituents from the stem extracts of Spatholobus parviflorus

Antibacterial and cytotoxic activities of phenolic constituents from the stem extracts of Spatholobus parviflorus

© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. A new 2-arylbenzofuran, spathobenzofuran (1), together with ten known compounds including a 2-arylbenzofuran, three pterocarpans and six isoflavones were isolated from the acetone crude extract of the stems of Spatholobus pa...

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Bibliographic Details
Main Authors: Thanika Promchai, Pawinee Janhom, Wisanu Maneerat, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Stephen G. Pyne, Thunwadee Limtharakul
Format: Journal
Published: 2020
Subjects:
Agricultural and Biological Sciences
Biochemistry, Genetics and Molecular Biology
Chemistry
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059066859&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70041
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Institution: Chiang Mai University
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Summary:© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. A new 2-arylbenzofuran, spathobenzofuran (1), together with ten known compounds including a 2-arylbenzofuran, three pterocarpans and six isoflavones were isolated from the acetone crude extract of the stems of Spatholobus parviflorus. All compounds were characterised by spectroscopic methods. Compound 4 was active (MIC 8 µg/mL) against Gram-negative Pseudomonas aeruginosa TISTR 781 while compound 2 had modest activity against Gram-positive Staphylococcus aureus TISTR 1466 with a MIC value of 16 µg/mL. All isolated compounds showed no cytotoxicity against Vero and KB cells.

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