Enhanced transdermal delivery of concentrated capsaicin from chili extract-loaded lipid nanoparticles with reduced skin irritation

• Main Authors: Phunsuk Anantaworasakul, Wantida Chaiyana, Bozena B. Michniak-Kohn, Wandee Rungseevijitprapa, Chadarat Ampasavate
• Format: Journal
• Published: 2020
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85085520120&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/71024
• Institution: Chiang Mai University

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The aim of this study was to develop lipid-based nanoparticles that entrapped a high concentration of capsaicin (0.25%) from a capsicum oleoresin extract. The solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) were stra...