LFA-1 on leukemic cells as a target for therapy or drug delivery

• Main Authors: Phongpradist R., Chittasupho C., Okonogi S., Siahaan T., Anuchapreeda S., Ampasavate C., Berkland C.
• Format: Review
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-77955646154&partnerID=40&md5=06dc1366bc28d9e7c18e115025c48368; http://www.ncbi.nlm.nih.gov/pubmed/20618153; http://cmuir.cmu.ac.th/handle/6653943832/740
• Institution: Chiang Mai University

Leukemia therapeutics are aiming for improved efficacy by targeting molecular markers differentially expressed on cancerous cells. Lymphocyte function-associated antigen-1 (LFA-1) expression on various types of leukemia has been well studied. Here, the role and expression of LFA-1 on leukemic cells...