Analysis of real-time PCR cycle threshold of alpha-thalassemia-1 Southeast Asian type deletion using fetal cell-free DNA in maternal plasma for noninvasive prenatal diagnosis of Bart's hydrops fetalis

• Main Authors: Pornprasert S., Sukunthamala K., Kunyanone N., Sittiprasert S., Thungkham K., Junorse S., Pongsawatkul K., Pattanaporn W., Jitwong C., Sanguansermsri T.
• Format: Comparative Study
• Language: English
• Published: 2014
• Online Access: http://www.ncbi.nlm.nih.gov/pubmed/3502482; http://cmuir.cmu.ac.th/handle/6653943832/806
• Institution: Chiang Mai University

Noninvasive prenatal diagnosis based on detection of fetal cell-free DNA is hampered when mother and father are both carriers for the same autosomal recessive mutation.