Pharmacogenetic markers of CYP2B6 associated with efavirenz plasma concentrations in HIV-1 infected Thai adults

• Main Authors: Sukasem C., Cressey T.R., Prapaithong P., Tawon Y., Pasomsub E., Srichunrusami C., Jantararoungtong T., Lallement M., Chantratita W.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-84869010225&partnerID=40&md5=7a0861c8f06a44bb979097ae19096049; http://cmuir.cmu.ac.th/handle/6653943832/904
• Institution: Chiang Mai University

Aims: To investigate the frequency of CYP2B6 polymorphisms and the influence of haplotype structure on plasma efavirenz concentrations in Thai adults with HIV-1 infection. Methods: Genotyping of nine single nucleotide polymorphisms (SNPs, c.64C>T, c.499C>G, c.516G>T, c.785A>G, c.1375A>...