INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
In twenty-four patients with acute falciparum malaria, the serum levels of fibrin-degradation products (F.D.P.) were studied. Eleven patients had cerebral malaria and in all of them serum-F.D.P. levels were greatly raised. In patients severely ill with jaundice or hyperpyrexia serum-F.D.P. concentra...
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| Format: | Article |
| Published: |
2018
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/10024 |
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| Institution: | Mahidol University |
| Summary: | In twenty-four patients with acute falciparum malaria, the serum levels of fibrin-degradation products (F.D.P.) were studied. Eleven patients had cerebral malaria and in all of them serum-F.D.P. levels were greatly raised. In patients severely ill with jaundice or hyperpyrexia serum-F.D.P. concentrations were also raised. In patients with uncomplicated falciparum malaria, serum-F.D.P. levels were normal or only slightly raised. One patient with cerebral malaria died and necropsy showed widespread fibrin thrombi in the capillaries of the brain and other viscera. Intravascular coagulation appears to be an important intermediary mechanism in severe falciparum malaria. © 1972. |
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