INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA

In twenty-four patients with acute falciparum malaria, the serum levels of fibrin-degradation products (F.D.P.) were studied. Eleven patients had cerebral malaria and in all of them serum-F.D.P. levels were greatly raised. In patients severely ill with jaundice or hyperpyrexia serum-F.D.P. concentra...

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Main Author: N. Jaroonvesama
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/10024
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spelling th-mahidol.100242018-03-12T15:42:05Z INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA N. Jaroonvesama Mahidol University Medicine In twenty-four patients with acute falciparum malaria, the serum levels of fibrin-degradation products (F.D.P.) were studied. Eleven patients had cerebral malaria and in all of them serum-F.D.P. levels were greatly raised. In patients severely ill with jaundice or hyperpyrexia serum-F.D.P. concentrations were also raised. In patients with uncomplicated falciparum malaria, serum-F.D.P. levels were normal or only slightly raised. One patient with cerebral malaria died and necropsy showed widespread fibrin thrombi in the capillaries of the brain and other viscera. Intravascular coagulation appears to be an important intermediary mechanism in severe falciparum malaria. © 1972. 2018-03-12T08:42:05Z 2018-03-12T08:42:05Z 1972-01-29 Article The Lancet. Vol.299, No.7744 (1972), 221-223 10.1016/S0140-6736(72)90621-6 01406736 2-s2.0-0015528023 https://repository.li.mahidol.ac.th/handle/123456789/10024 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0015528023&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
N. Jaroonvesama
INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
description In twenty-four patients with acute falciparum malaria, the serum levels of fibrin-degradation products (F.D.P.) were studied. Eleven patients had cerebral malaria and in all of them serum-F.D.P. levels were greatly raised. In patients severely ill with jaundice or hyperpyrexia serum-F.D.P. concentrations were also raised. In patients with uncomplicated falciparum malaria, serum-F.D.P. levels were normal or only slightly raised. One patient with cerebral malaria died and necropsy showed widespread fibrin thrombi in the capillaries of the brain and other viscera. Intravascular coagulation appears to be an important intermediary mechanism in severe falciparum malaria. © 1972.
author2 Mahidol University
author_facet Mahidol University
N. Jaroonvesama
format Article
author N. Jaroonvesama
author_sort N. Jaroonvesama
title INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
title_short INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
title_full INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
title_fullStr INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
title_full_unstemmed INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA
title_sort intravascular coagulation in falciparum malaria
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/10024
_version_ 1763489117161652224