Candidate gene association analysis of acute lymphoblastic leukemia identifies new susceptibility locus at 11p15 (LMO1)

• Main Authors: Joke Beuten, Jonathan A L Gelfond, Duangjai Piwkham, Brad H. Pollock, Naomi J. Winick, Anderson B. Collier, Gail E. Tomlinson
• Other Authors: University of Texas Health Science Center at San Antonio
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/11474
• Institution: Mahidol University

To determine the contribution of susceptibility loci in explaining the genetic basis of acute lymphoblastic leukemia (ALL), we genotyped 29 high-potential candidate genes with 672 tagged single-nucleotide polymorphisms (SNPs) in a sample (163 cases and 251 healthy controls) of Caucasian children. Fi...