Effect of storage levels of nitric oxide derivatives in blood components

• Main Authors: Alan N. Schechter, Melissa A. Qazi, Fabiola Rizzatti, Barbora Piknova, Nathawut Sibmooh, David F. Stroncek
• Other Authors: National Institute of Diabetes and Digestive and Kidney Diseases
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13589
• Institution: Mahidol University

Background: Potential deleterious effects of red blood cell (RBC) transfusions, especially from blood kept at length, have been ascribed to biochemical changes during storage, including those of nitric oxide (NO) metabolism. Study methods and design: In this study, NO metabolites, nitrite and nitrat...