Proteomic identification of a direct role for cyclin D1 in DNA damage repair

The human CCND1 gene, which encodes the cell-cycle protein cyclin D1, is one of the most frequently amplified genes in human cancers. Cyclin D1 activates the cyclin-dependent kinases CDK4 and CDK6 and drives cell proliferation. Beyond the cell-cycle role, the full repertoire of cyclin D1 functions i...

Full description

Saved in:
Bibliographic Details
Main Authors: Siwanon Jirawatnotai, Yiduo Hu, David M. Livingston, Piotr Sicinski
Other Authors: Harvard Medical School
Format: Review
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/13625
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University