Proteomic identification of a direct role for cyclin D1 in DNA damage repair
The human CCND1 gene, which encodes the cell-cycle protein cyclin D1, is one of the most frequently amplified genes in human cancers. Cyclin D1 activates the cyclin-dependent kinases CDK4 and CDK6 and drives cell proliferation. Beyond the cell-cycle role, the full repertoire of cyclin D1 functions i...
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Main Authors: | Siwanon Jirawatnotai, Yiduo Hu, David M. Livingston, Piotr Sicinski |
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Other Authors: | Harvard Medical School |
Format: | Review |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/13625 |
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Institution: | Mahidol University |
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