Cyclin D1 depletion interferes with oxidative balance and promotes cancer cell senescence

Cyclin D1 depletion interferes with oxidative balance and promotes cancer cell senescence

© 2018. Published by The Company of Biologists Ltd. Expression of cyclin D1 (CCND1) is required for cancer cell survival and proliferation. This is presumably due to the role of cyclin D1 in inactivation of the RB tumor suppressor. Here, we investigated the pro-survival function of cyclin D1 in a nu...

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Bibliographic Details
Main Authors: Phatthamon Laphanuwat, Pornlada Likasitwatanakul, Gunya Sittithumcharee, Araya Thaphaengphan, Nussara Chomanee, Orawan Suppramote, Nuttavadee Ketaroonrut, Komgrid Charngkaew, Eric W.F. Lam, Seiji Okada, Uraiwan Panich, Somponnat Sampattavanich, Siwanon Jirawatnotai
Other Authors: Kumamoto University
Format: Article
Published: 2019
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/45152
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/45152

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