Chitosan and its quaternized derivative as effective long dsRNA carriers targeting shrimp virus in Spodoptera frugiperda 9 cells

• Main Authors: Gatesara Theerawanitchpan, Nattika Saengkrit, Warayuth Sajomsang, Pattarapond Gonil, Uracha Ruktanonchai, Somsak Saesoo, Timothy W. Flegel, Vanvimon Saksmerprome
• Other Authors: Center of Excellence for Shrimp Molecular Biology and Biotechnology (Centex Shrimp)
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13631
• Institution: Mahidol University

RNA interference (RNAi) is a promising strategy to combat shrimp viral pathogens at lab-scale experiments. Development of effective orally delivered agents for double-stranded (ds)RNA is necessary for RNAi application at farm level. Since continuous shrimp cell lines have not been established, we ar...