Ni 2 +-activated glyoxalase i from Escherichia coli: Substrate specificity, kinetic isotope effects and evolution within the βαβββ superfamily

The Escherichia coli glyoxalase system consists of the metalloenzymes glyoxalase I and glyoxalase II. Little is known regarding Ni 2 + -activated E. coli glyoxalase I substrate specificity, its thiol cofactor preference, the presence or absence of any substrate kinetic isotope effects on the enzyme...

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Bibliographic Details
Main Authors: Kadia Y. Mullings, Nicole Sukdeo, Uthaiwan Suttisansanee, Yanhong Ran, John F. Honek
Other Authors: University of Waterloo
Format: Conference or Workshop Item
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/13790
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Institution: Mahidol University