Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis

Autoantibodies with the highest specificity for rheumatoid arthritis (RA) are the antibodies directed to citrulline-containing epitopes, so-called anti-citrullinated peptide/protein antibodies (ACPA). During the past decade it became clear that the presence of these antibodies was highly predictive...

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Main Authors: Parawee Suwannalai, Leendert A. Trouw, Rene E.M. Toes, Tom W.J. Huizinga
Other Authors: Leiden University Medical Center - LUMC
Format: Review
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/14999
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spelling th-mahidol.149992018-06-11T12:17:11Z Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis Parawee Suwannalai Leendert A. Trouw Rene E.M. Toes Tom W.J. Huizinga Leiden University Medical Center - LUMC Mahidol University Medicine Autoantibodies with the highest specificity for rheumatoid arthritis (RA) are the antibodies directed to citrulline-containing epitopes, so-called anti-citrullinated peptide/protein antibodies (ACPA). During the past decade it became clear that the presence of these antibodies was highly predictive of and specific for RA, and illustrating the importance of ACPA. Therefore, the presence of these antibodies is one of the new American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) 2010 criteria for RA. Apart from the presence of these antibodies, the composition of this antibody response matures during RA development. This review summarizes the current knowledge of the characteristics of ACPA in RA development. © Japan College of Rheumatology 2011. 2018-06-11T05:17:11Z 2018-06-11T05:17:11Z 2012-02-01 Review Modern Rheumatology. Vol.22, No.1 (2012), 15-20 10.1007/s10165-011-0486-8 14397609 14397595 2-s2.0-84861478682 https://repository.li.mahidol.ac.th/handle/123456789/14999 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861478682&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Parawee Suwannalai
Leendert A. Trouw
Rene E.M. Toes
Tom W.J. Huizinga
Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
description Autoantibodies with the highest specificity for rheumatoid arthritis (RA) are the antibodies directed to citrulline-containing epitopes, so-called anti-citrullinated peptide/protein antibodies (ACPA). During the past decade it became clear that the presence of these antibodies was highly predictive of and specific for RA, and illustrating the importance of ACPA. Therefore, the presence of these antibodies is one of the new American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) 2010 criteria for RA. Apart from the presence of these antibodies, the composition of this antibody response matures during RA development. This review summarizes the current knowledge of the characteristics of ACPA in RA development. © Japan College of Rheumatology 2011.
author2 Leiden University Medical Center - LUMC
author_facet Leiden University Medical Center - LUMC
Parawee Suwannalai
Leendert A. Trouw
Rene E.M. Toes
Tom W.J. Huizinga
format Review
author Parawee Suwannalai
Leendert A. Trouw
Rene E.M. Toes
Tom W.J. Huizinga
author_sort Parawee Suwannalai
title Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
title_short Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
title_full Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
title_fullStr Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
title_full_unstemmed Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
title_sort anti-citrullinated protein antibodies (acpa) in early rheumatoid arthritis
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/14999
_version_ 1763487878015352832

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