Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis

• Main Authors: Parawee Suwannalai, Leendert A. Trouw, Rene E.M. Toes, Tom W.J. Huizinga
• Other Authors: Leiden University Medical Center - LUMC
• Format: Review
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/14999
• Institution: Mahidol University

Autoantibodies with the highest specificity for rheumatoid arthritis (RA) are the antibodies directed to citrulline-containing epitopes, so-called anti-citrullinated peptide/protein antibodies (ACPA). During the past decade it became clear that the presence of these antibodies was highly predictive...