Influence of ABCB-1 C3435T polymorphisms on plasma nevirapine and efavirenz levels and their effects on virologic and immunological outcomes in HIV/TB co-infected thai adults under anti-retroviral therapy

Influence of ABCB-1 C3435T polymorphisms on plasma nevirapine and efavirenz levels and their effects on virologic and immunological outcomes in HIV/TB co-infected thai adults under anti-retroviral therapy

ATP-binding cassette, sub-family B (encoded by ABCB-1or MDR-1) has an important role in cellular export of antiretroviral agents. A previous study showed that ABCB-1 C3435T polymorphism affects plasma efavirenz and nelfinavir concentrations and rate of CD4+ T cell recovery after starting antiretrovi...

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Bibliographic Details
Main Authors: Sumonmal Uttayamakul, Sirirat Likanonsakul, Weerawat Manosuthi, Nuanjun Wichukchinda, Tatsuo Shioda, Srisin Khusmith
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/15099
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/15099

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