Azadirachtin derivatives from seed kernels of Azadirachta excelsa

Three new azadirachtin derivatives, named azadirachtins O-Q (1-3), along with the known azadirachtin B (4), azadirachtin L (5), azadirachtin M (6) 11α-azadirachtin H (7), 11β-azadirachtin H (8), and azadirachtol (9) were isolated from seed kernels of Azadirachta excelsa. Their structures were establ...

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Main Authors:	Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Thirada Prajuabsuk, Sanha Panichajakul, Piyanan Panyamee, Samran Prabpai, Palangpon Kongsaeree
Other Authors:	Khon Kaen University
Format:	Article
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/16322
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Institution:	Mahidol University

id	th-mahidol.16322
record_format	dspace
spelling	th-mahidol.163222018-06-21T15:34:05Z Azadirachtin derivatives from seed kernels of Azadirachta excelsa Somdej Kanokmedhakul Kwanjai Kanokmedhakul Thirada Prajuabsuk Sanha Panichajakul Piyanan Panyamee Samran Prabpai Palangpon Kongsaeree Khon Kaen University Mahidol University Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Three new azadirachtin derivatives, named azadirachtins O-Q (1-3), along with the known azadirachtin B (4), azadirachtin L (5), azadirachtin M (6) 11α-azadirachtin H (7), 11β-azadirachtin H (8), and azadirachtol (9) were isolated from seed kernels of Azadirachta excelsa. Their structures were established by spectroscopic techniques, and the structure of 3 was confirmed by X-ray analysis. Compounds 1-7 and 9 exhibited toxicity to the diamondback moth (Plutella xylostella) with an LD50 of 0.75-1.92 μg/g body weight, in 92 h. © 2005 American Chemical Society and American Society of Pharmacognosy. 2018-06-21T08:08:52Z 2018-06-21T08:08:52Z 2005-07-01 Article Journal of Natural Products. Vol.68, No.7 (2005), 1047-1050 10.1021/np050064t 01633864 2-s2.0-23844514717 https://repository.li.mahidol.ac.th/handle/123456789/16322 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23844514717&origin=inward
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Medicine Pharmacology, Toxicology and Pharmaceutics Somdej Kanokmedhakul Kwanjai Kanokmedhakul Thirada Prajuabsuk Sanha Panichajakul Piyanan Panyamee Samran Prabpai Palangpon Kongsaeree Azadirachtin derivatives from seed kernels of Azadirachta excelsa
description	Three new azadirachtin derivatives, named azadirachtins O-Q (1-3), along with the known azadirachtin B (4), azadirachtin L (5), azadirachtin M (6) 11α-azadirachtin H (7), 11β-azadirachtin H (8), and azadirachtol (9) were isolated from seed kernels of Azadirachta excelsa. Their structures were established by spectroscopic techniques, and the structure of 3 was confirmed by X-ray analysis. Compounds 1-7 and 9 exhibited toxicity to the diamondback moth (Plutella xylostella) with an LD50 of 0.75-1.92 μg/g body weight, in 92 h. © 2005 American Chemical Society and American Society of Pharmacognosy.
author2	Khon Kaen University
author_facet	Khon Kaen University Somdej Kanokmedhakul Kwanjai Kanokmedhakul Thirada Prajuabsuk Sanha Panichajakul Piyanan Panyamee Samran Prabpai Palangpon Kongsaeree
format	Article
author	Somdej Kanokmedhakul Kwanjai Kanokmedhakul Thirada Prajuabsuk Sanha Panichajakul Piyanan Panyamee Samran Prabpai Palangpon Kongsaeree
author_sort	Somdej Kanokmedhakul
title	Azadirachtin derivatives from seed kernels of Azadirachta excelsa
title_short	Azadirachtin derivatives from seed kernels of Azadirachta excelsa
title_full	Azadirachtin derivatives from seed kernels of Azadirachta excelsa
title_fullStr	Azadirachtin derivatives from seed kernels of Azadirachta excelsa
title_full_unstemmed	Azadirachtin derivatives from seed kernels of Azadirachta excelsa
title_sort	azadirachtin derivatives from seed kernels of azadirachta excelsa
publishDate	2018
url	https://repository.li.mahidol.ac.th/handle/123456789/16322
_version_	1763487478953541632

Azadirachtin derivatives from seed kernels of Azadirachta excelsa

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