Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression
(S)-Adenosylmethionine (SAM) is a critical element of melatonin synthesis as the methyl donor in the last step of the pathway, the O-methylation of N-acetyl 5-hydroxytryptamine by hydroxyindole-O-methyltransferase. The activity of the enzyme that synthesizes SAM, methionine adenosyltransferase (MAT)...
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Main Authors: | Jong So Kim, Steven L. Coon, Seth Blackshaw, Constance L. Cepko, Morten Møller, Sujira Mukda, Wan Qian Zhao, Clivel G. Charlton, David C. Klein |
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Other Authors: | National Institute of Child Health and Human Development |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/16385 |
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Institution: | Mahidol University |
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