Potentiation of carbon tetrachloride hepatotoxicity by piperine

The effect of piperine on CCl4-induced hepatotoxicity was investigated in rats. Piperine pretreatment potentiated the hepatotoxicity of CCI4 in a dose-dependent manner. The maximum potentiation occurred when piperine at a dose of 100 mg/kg BW was intragastrically administered 4 h prior to an intrape...

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Bibliographic Details
Main Authors: P. Piyachaturawat, S. Kingkaeohoi, C. Toskulkao
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/17267
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Institution: Mahidol University