Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD?
Our study suggests that the administration of bronchodilator drug via nebulizer powered by flow rate 6 L/min is more suitable in COPD patients. The oxygen flow rates should not be given more than 6 L/min. In this study, we recruited COPD patients in a stable stage, in whom the risk of hyperoxic indu...
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th-mahidol.173492018-07-04T13:55:51Z Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? S. Charoenratanakul K. Borrirukwanit W. Satayawiwat S. Lekuthai W. Dejsomritrutai Mahidol University Medicine Our study suggests that the administration of bronchodilator drug via nebulizer powered by flow rate 6 L/min is more suitable in COPD patients. The oxygen flow rates should not be given more than 6 L/min. In this study, we recruited COPD patients in a stable stage, in whom the risk of hyperoxic induced hypercarbia is less than in the acute exacerbation stage. Thus, in acute exacerbation stage of the COPD patients, the rise of carbon-dioxide should be higher. We recommend that the COPD patients should receive bronchodilator drug via the nebulizer, especially in acute exacerbation stage, with oxygen flow rate not more than 6 L/min. The medical personnel must closely observe the clinical signs of the patients to prevent the hazard of carbon-dioxide retention. 2018-07-04T06:55:51Z 2018-07-04T06:55:51Z 1995-12-01 Article Journal of the Medical Association of Thailand. Vol.78, No.12 (1995), 670-677 01252208 2-s2.0-0029552450 https://repository.li.mahidol.ac.th/handle/123456789/17349 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0029552450&origin=inward |
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Medicine S. Charoenratanakul K. Borrirukwanit W. Satayawiwat S. Lekuthai W. Dejsomritrutai Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? |
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Our study suggests that the administration of bronchodilator drug via nebulizer powered by flow rate 6 L/min is more suitable in COPD patients. The oxygen flow rates should not be given more than 6 L/min. In this study, we recruited COPD patients in a stable stage, in whom the risk of hyperoxic induced hypercarbia is less than in the acute exacerbation stage. Thus, in acute exacerbation stage of the COPD patients, the rise of carbon-dioxide should be higher. We recommend that the COPD patients should receive bronchodilator drug via the nebulizer, especially in acute exacerbation stage, with oxygen flow rate not more than 6 L/min. The medical personnel must closely observe the clinical signs of the patients to prevent the hazard of carbon-dioxide retention. |
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Mahidol University |
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Mahidol University S. Charoenratanakul K. Borrirukwanit W. Satayawiwat S. Lekuthai W. Dejsomritrutai |
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Article |
author |
S. Charoenratanakul K. Borrirukwanit W. Satayawiwat S. Lekuthai W. Dejsomritrutai |
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S. Charoenratanakul |
title |
Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? |
title_short |
Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? |
title_full |
Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? |
title_fullStr |
Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? |
title_full_unstemmed |
Is driving oxygen flow rate clinically important for nebulizer therapy in patients with COPD? |
title_sort |
is driving oxygen flow rate clinically important for nebulizer therapy in patients with copd? |
publishDate |
2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/17349 |
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1763488561188831232 |