A single dose of vero cell-derived Japanese encephalitis (JE) vaccine (Ixiaro) effectively boosts immunity in travelers primed with mouse brain-derived JE vaccines.

• Main Authors: Elina O. Erra, Helena Hervius Askling, Lars Rombo, Jukka Riutta, Sirkka Vene, Sutee Yoksan, Lars Lindquist, Pakkanen, Sari H., Eili Huhtamo, Olli Vapalahti, Anu Kantele
• Other Authors: Mahidol University. Faculty of Medicine. Haartman Institute
• Format: Article
• Language: English
• Published: 2015
• Subjects: Single Dose; Vero Cell–Derived; Japanese; (JE); Vaccine; (Ixiaro); Effectively Boosts Immunity; Mouse Brain–Derived; Vaccines; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/1822
• Institution: Mahidol University

BACKGROUND: A significant part of the world population lives in areas with endemic Japanese encephalitis (JE). For travelers from nonendemic countries, Vero cell-derived vaccine (JE-VC; Ixiaro) has replaced traditional mouse brain-derived vaccines (JE-MB) associated with safety concerns. The 2 vacc...