Physicochemical properties and biocompatibility of N-trimethyl chitosan: Effect of quaternization and dimethylation

• Main Authors: Anchalee Jintapattanakit, Shirui Mao, Thomas Kissel, Varaporn Buraphacheep Junyaprasert
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/18852

The aim of this research was to investigate the effect of degrees of quaternization (DQ) and dimethylation (DD) on physicochemical properties and cytotoxicity of N-trimethyl chitosan (TMC). TMC was synthesized by reductive methylation of chitosan in the presence of a strong base at elevated temperat...