Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I

The syntheses of indolizidine alkaloids, i.e., (±)-coniceine, (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I via Pummerer cyclization are described. The key step is the transformation of lactam sulfoxide to bicyclic lactam via the Pummerer cyclization. © 2007 Elsevier Ltd. All r...

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Main Authors:	Chutima Kuhakarn, Phachanee Seehasombat, Thaworn Jaipetch, Manat Pohmakotr, Vichai Reutrakul
Other Authors:	Mahidol University
Format:	Article
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/18969
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Institution:	Mahidol University

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spelling	th-mahidol.189692018-07-12T09:51:35Z Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I Chutima Kuhakarn Phachanee Seehasombat Thaworn Jaipetch Manat Pohmakotr Vichai Reutrakul Mahidol University Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics The syntheses of indolizidine alkaloids, i.e., (±)-coniceine, (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I via Pummerer cyclization are described. The key step is the transformation of lactam sulfoxide to bicyclic lactam via the Pummerer cyclization. © 2007 Elsevier Ltd. All rights reserved. 2018-07-12T02:19:44Z 2018-07-12T02:19:44Z 2008-02-18 Article Tetrahedron. Vol.64, No.8 (2008), 1663-1670 10.1016/j.tet.2007.12.013 00404020 2-s2.0-38349057328 https://repository.li.mahidol.ac.th/handle/123456789/18969 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=38349057328&origin=inward
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Pharmacology, Toxicology and Pharmaceutics Chutima Kuhakarn Phachanee Seehasombat Thaworn Jaipetch Manat Pohmakotr Vichai Reutrakul Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I
description	The syntheses of indolizidine alkaloids, i.e., (±)-coniceine, (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I via Pummerer cyclization are described. The key step is the transformation of lactam sulfoxide to bicyclic lactam via the Pummerer cyclization. © 2007 Elsevier Ltd. All rights reserved.
author2	Mahidol University
author_facet	Mahidol University Chutima Kuhakarn Phachanee Seehasombat Thaworn Jaipetch Manat Pohmakotr Vichai Reutrakul
format	Article
author	Chutima Kuhakarn Phachanee Seehasombat Thaworn Jaipetch Manat Pohmakotr Vichai Reutrakul
author_sort	Chutima Kuhakarn
title	Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I
title_short	Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I
title_full	Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I
title_fullStr	Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I
title_full_unstemmed	Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I
title_sort	synthesis of alkylated indolizidine alkaloids via pummerer mediated cyclization: synthesis of (±)-indolizidine 167b, (±)-5-butylindolizidine and (±)-monomorine i
publishDate	2018
url	https://repository.li.mahidol.ac.th/handle/123456789/18969
_version_	1763497711743533056

Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I

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