Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax

Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax

The genes encoding the wild-type and six (five single and one double) mutant dihydrofolate reductase (DHFR) domains of the human malaria parasite, Plasmodium vivax (Pv), were cloned and expressed in Escherichia coli. The catalytic activities and the kinetic parameters of the purified recombinant wil...

Full description

Saved in:
Bibliographic Details
Main Authors: Ubolsree Leartsakulpanich, Mallika Imwong, Sasithon Pukrittayakamee, Nicholas J. White, Georges Snounou, Worachart Sirawaraporn, Yongyuth Yuthavong
Other Authors: Thailand National Center for Genetic Engineering and Biotechnology
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/20087
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/20087

Similar Items