Dihydrofolate reductase and antifolate resistance in malaria

بواسطة Worachart Sirawaraporn
منشور في 2018

Kinetic and molecular properties of dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

بواسطة Worachart Sirawaraporn, Yongyuth Yuthavong
منشور في 2018

Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase

بواسطة Natpasit Chaianantakul, Rachada Sirawaraporn, Worachart Sirawaraporn
منشور في 2018

Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase

بواسطة Natpasit Chaianantakul, Rachada Sirawaraporn, Worachart Sirawaraporn
منشور في 2017

Pyrimethamine analogue inhibitors of resistance mutants of Plasmodial dihydrofolate reductase

بواسطة Ali Sardarian, Kenneth T. Douglas, Penchit Chitnumsub, Worachart Sirawaraporn
منشور في 2018

Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthase

بواسطة Yuwadee Talawanich, Sumalee Kamchonwongpaisan, Worachart Sirawaraporn, Yongyuth Yuthavong
منشور في 2018

Probing the roles of non-homologous insertions in the N-terminal domain of Plasmodium falciparum hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase

بواسطة Woraphol Rattanachuen, Maria Jönsson, Göte Swedberg, Worachart Sirawaraporn
منشور في 2018

Purification and properties of recombinant Pneumocystis carinii dihydrofolate reductase

بواسطة Worachart Sirawaraporn, Jeffrey C. Edman, Daniel V. Santi
منشور في 2018

Molecular dynamics simulation of the human apo-dihydrofolate reductase: An investigation of an unstable enzyme

بواسطة Pornthep Sompornpisut, Atchara Wijitkosoom, Vudhichai Parasuk, Worachart Sirawaraporn
منشور في 2018

Chemical synthesis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

بواسطة Phisit Prapunwattana, Worachart Sirawaraporn, Yongyuth Yuthavong, Daniel V. Santi
منشور في 2018

Novel antifolate resistant mutations of Plasmodium falciparum dihydrofolate reductase selected in Escherichia coli

بواسطة Sudsanguan Chusacultanachai, Pornpan Thiensathit, Bongkoch Tarnchompoo, Worachart Sirawaraporn, Yongyuth Yuthavong
منشور في 2018

Analysis in Escherichia coli of Plasmodium falciparum dihydropteroate synthase (DHPS) alleles implicated in resistance to sulfadoxine

بواسطة Janette Berglez, Peter Iliades, Worachart Sirawaraporn, Peter Coloe, Ian Macreadie
منشور في 2018

Cloning and expression of Mycobacterium tuberculosis and Mycobacterium leprae dihydropteroate synthase in Escherichia coli

بواسطة Vanida Nopponpunth, Worachart Sirawaraporn, Patricia J. Greene, Daniel V. Santi
منشور في 2018

Plasmodium falciparum: Asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant

بواسطة Worachart Sirawaraporn, Suganya Yongkiettrakul, Rachada Sirawaraporn, Yongyuth Yuthavong, Daniel V. Santi
منشور في 2018

Specificity in structure-based drug design: Identification of a novel, selective inhibitor of Pneumocystis carinii dihydrofolate reductase

بواسطة Daniel A. Gschwend, Worachart Sirawaraporn, Daniel V. Santi, Irwin D. Kuntz
منشور في 2018

Molecular characterization of bifunctional hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase from Plasmodium falciparum

بواسطة Waraporn Kasekarn, Rachada Sirawaraporn, Thippayarat Chahomchuen, Alan F. Cowman, Worachart Sirawaraporn
منشور في 2018

Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

بواسطة Worachart Sirawaraporn, Tanajit Sathitkul, Rachada Sirawaraporn, Yongyuth Yuthavong, Daniel V. Santi
منشور في 2018

Synthesis of solution-phase combinatorial library of 4,6-diamino-1,2-dihydro-1,3,5-triazine and identification of new leads against A16V+S108T mutant dihydrofolate reductase of Pla...

بواسطة Tirayut Vilaivan, Neungruthai Saesaengseerung, Deanpen Jarprung, Sumalee Kamchonwongpaisan, Worachart Sirawaraporn, Yongyuth Yuthavong
منشور في 2018

Heterologous Expression of Active Thymidylate Synthase–Dihydrofolate Reductase from Plasmodium falciparum

بواسطة Worachart Sirawaraporn, Rachada Sirawaraporn, Yongyuth Yuthavong, Alan F. Cowman, Daniel V. Santi
منشور في 2018

Purification and characterization of dihydrofolate reductase from wild-type and trimethoprim-resistant Mycobacterium smegmatis

بواسطة Worachart Sirawaraporn, Rachada Sirawaraporn, Atid Chanpongsri, William R. Jacobs, Daniel V. Santi
منشور في 2018