Kinetic and molecular properties of dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

Dihydrofolate reductase (5,6,7,8-tetrahydrofolate: NADP+oxidoreductase, EC 1.5.1.3) was partially purified from a cloned strain of pyrimethamine-sensitive Plasmodium chabaudi and a drug-resistant clone derived from it. A molecular weight of approximately 120 000 was estimated by gel filtration for e...

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Bibliographic Details
Main Authors: Worachart Sirawaraporn, Yongyuth Yuthavong
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/30575
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Institution: Mahidol University