Treatment of uncomplicated multidrug-resistant falciparum malaria with artesunate-atovaquone-proguanil

• Main Authors: Michèle Van Vugt, Elisabetta Leonardi, Lucy Phaipun, Thra Slight, Kyaw Lay Thway, Rose McGready, Alan Brockman, Leopoldo Villegas, Sornchai Looareesuwan, Nicholas J. White, Franc̃ois Nosten
• Other Authors: Shoklo Malaria Research Unit
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20175
• Institution: Mahidol University

In an open-label trial carried out on the northwest border of Thailand, 1596 patients with uncomplicated multidrug-resistant falciparum malaria were randomly assigned to receive atovaquone-proguanil, atovaquone-proguanil-artesunate, or artesunate-mefloquine and were followed up for 42 days. All 3 re...