Rapid genotyping of loci involved in antifolate drug resistance in Plasmodium falciparum by primer extension

Current methods used to genotype point mutations in Plasmodium falciparum genes involved in resistance to antifolate drugs include restriction digestion of PCR products, allele-specific amplification or sequencing. Here we demonstrate that known point mutations in dihydrofolate reductase and dihydro...

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Bibliographic Details
Main Authors: Shalini Nair, Alan Brockman, Lucy Paiphun, François Nosten, Tim J C Anderson
Other Authors: Texas Biomedical Research Institute
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/20205
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Institution: Mahidol University