Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever

• Main Authors: Juthathip Mongkolsapaya, Wanwisa Dejnirattisai, Xiao Ning Xu, Sirijitt Vasanawathana, Nattaya Tangthawornchaikul, Aroonrung Chairunsri, Siraporn Sawasdivorn, Thaneeya Duangchinda, Tao Dong, Sarah Rowland-Jones, Pa Thai Yenchitsomanus, Andrew McMichael, Prida Malasit, Gavin Screaton
• Other Authors: John Radcliffe Hospital
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20715
• Institution: Mahidol University

Dengue virus presents a growing threat to public health in the developing world. Four major serotypes of dengue virus have been characterized, and epidemiological evidence shows that dengue hemorrhagic fever (DHF), the more serious manifestation of the disease, occurs more frequently upon reinfectio...