T cell responses in dengue hemorrhagic fever: Are cross-reactive T cells suboptimal?

• Main Authors: Juthathip Mongkolsapaya, Thaneeya Duangchinda, Wanwisa Dejnirattisai, Sirijit Vasanawathana, Panisadee Avirutnan, Aroonroong Jairungsri, Nuanpan Khemnu, Nattaya Tangthawornchaikul, Pojchong Chotiyarnwong, Kanokwan Sae-Jang, Michael Koch, Yvonne Jones, Andrew McMichael, Xiaoning Xu, Prida Malasit, Gavin Screaton
• Other Authors: Hammersmith Hospital
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23352
• Institution: Mahidol University

Dengue virus infection poses a growing public health and economic burden in a number of tropical and subtropical countries. Dengue circulates as a number of quasispecies, which can be divided by serology into four groups or serotypes. An interesting feature of Dengue, recognized over five decades ag...