Clinical trial of oral artesunate with or without high-dose primaquine for the treatment of vivax malaria in Thailand.

• Main Authors: Udomsak Silachamroon, Srivicha Krudsood, Sombat Treeprasertsuk, Polrat Wilairatana, Kobsiri Chalearmrult, Hla Yin Mint, Pannamas Maneekan, Nicholas J. White, Victor R. Gourdeuk, Gary M. Brittenham, Sornchai Looareesuwan
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20895

We studied prospectively 801 Thai patients admitted to the Bangkok Hospital for Tropical Diseases with acute, symptomatic Plasmodium vivax malaria to determine the optimum duration of treatment with oral artesunate and the safety, tolerability, and effectiveness of a high dose of primaquine in preve...