In-vitro response of Plasmodium falciparum to the main alkaloids of Cinchona in northwestern Thailand

• Main Authors: Ariane Knauer, Jeeraphat Sirichaisinthop, Franz F. Reinthaler, Gerhard Wiedermann, Gunther Wernsdorfer, Walther H. Wernsdorfer
• Other Authors: Karl-Franzens-Universitat Graz
• Format: Conference or Workshop Item
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20998
• Institution: Mahidol University

The blood schizontocidal activity of the four main Cinchona alkaloids against Plasmodium falciparum was compared in 46 fresh parasite isolates, using an in-vitro test measuring the drug-specific inhibition of schizont maturation. The studies were conducted in June-August 2001 at Mae Sot, northwester...