Real-time PCR for dihydrofolate reductase gene single-nucleotide polymorphisms in Plasmodium vivax isolates

• Main Authors: Sara Brega, Frédérique De Monbrison, Carlo Severini, Rachanee Udomsangpetch, Inge Sutanto, Paul Ruckert, François Peyron, Stéphane Picot
• Other Authors: Universite Claude Bernard, Faculte de Medecine RTH Laennec
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/21619
• Institution: Mahidol University

Mutations in the dhfr gene of Plasmodium vivax (pvdhfr) are associated with resistance to the antifolate antimalarial drugs. Polymorphisms in the pvdhfr gene were assessed by hybridization probe technology on the LightCycler instrument with 134 P. vivax-infected blood samples from Turkey (n = 24), A...