Dose-dependent effects of 2-acetylaminofluorene on hepatic foci development and cell proliferation in rats
Dose-dependent development of pre-neoplastk liver cell foci induced by 2-acetylaminofluorene (2-AAF) was investigated in relation to cell-proliferative activity. Male F344 rats were initially given a single i.p. injection of diethylnitrosamine (DEN, 200 mg/kg) and starting 2 weeks later received die...
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Main Authors: | Danai Tiwawech, Ryohei Hasegawa, Yasushi Kurata, Masae Tatematsu, Masa Aki Shibata, Witaya Thamavit, Nobuyuki Ito |
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Other Authors: | Nagoya City University Medical School |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/21986 |
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Institution: | Mahidol University |
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