Pyrimethamine resistant mutations in Plasmodium falciparum

Pyrimethamine resistant mutations in Plasmodium falciparum

Three mutations in Plasmodium falciparum yielding increased resistance to pyrimethamine were obtained following treatment with chemical mutagens and selection in presence of pyrimethamine. From parasite clone TM4/8.2 a mutant, TM4/8.2/4.1, was produced which raised pyrimethamine resistance about 500...

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Bibliographic Details
Main Authors: Sodsri Thaithong, Shiu Wan Chan, Supasorn Songsomboon, Prapon Wilairat, Nowarat Seesod, Tada Sueblinwong, Michael Goman, Robert Ridley, Geoffrey Beale
Other Authors: Chulalongkorn University
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/22275
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/22275

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