Trafficking defect of mutant kidney anion exchanger 1 (kAE1) proteins associated with distal renal tubular acidosis and Southeast Asian ovalocytosis

• Main Authors: Nunghathai Sawasdee, Wandee Udomchaiprasertkul, Sansanee Noisakran, Nanyawan Rungroj, Varaporn Akkarapatumwong, Pa thai Yenchitsomanus
• Other Authors: Division of Medical Molecular Biology
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/22947
• Institution: Mahidol University

Compound heterozygous anion exchanger 1 (AE1) SAO/G701D mutations result in distal renal tubular acidosis with Southeast Asian ovalocytosis. Interaction, trafficking and localization of wild-type and mutant (SAO and G701D) kAE1 proteins fused with hemagglutinin, six-histidine, Myc, or green fluoresc...