Transmembrane protein 139 (TMEM139) interacts with human kidney isoform of anion exchanger 1 (kAE1)

• Main Authors: Nalin On Nuiplot, Mutita Junking, Natapol Duangtum, Sasiprapa Khunchai, Nunghathai Sawasdee, Pa Thai Yenchitsomanus, Varaporn Akkarapatumwong
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35424

© 2015 Elsevier Inc.All rights reserved. Human kidney anion exchanger 1 (kAE1) mediates Cl-/HCO3-exchanges at the basolateral membrane of the acid-secreting α-intercalated cells. Mutations in SLC4A1 gene encoding kAE1 are associated with distal renal tubular acidosis (dRTA). Several studies have sho...