High rate multiple drug resistances in HIV-infected patients failing nonnucleoside reverse transcriptase inhibitor regimens in Thailand, where subtype A/E is predominant

• Main Authors: Ploenchan Chetchotisakd, Siriluck Anunnatsiri, Sasisopin Kiertiburanakul, Ruengpung Sutthent, Thanomsak Anekthananon, Chureeratana Bowonwatanuwong, Boonchai Kowadisaiburana, Khuanchai Supparatpinyo, Manassinee Horsakulthai, Sanchai Chasombat, Kiat Ruxrungtham
• Other Authors: Khon Kaen University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23285
• Institution: Mahidol University

The prevalence of drug resistance was determined among 64 HIV-infected Thai patients who were failed while receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Eighty-nine percent of patients had 1 or more NNRTI mutation resistances. Almost all patients had resistance to a...