High rate multiple drug resistances in HIV-infected patients failing nonnucleoside reverse transcriptase inhibitor regimens in Thailand, where subtype A/E is predominant

• Main Authors: Ploenchan Chetchotisakd, Siriluck Anunnatsiri, Sasisopin Kiertiburanakul, Ruengpung Sutthent, Thanomsak Anekthananon, Chureeratana Bowonwatanuwong, Boonchai Kowadisaiburana, Khuanchai Supparatpinyo, Manassinee Horsakulthai, Sanchai Chasombat, Kiat Ruxrungtham
• Format: Journal
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=35448999929&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61708
• Institution: Chiang Mai University

The prevalence of drug resistance was determined among 64 HIV-infected Thai patients who were failed while receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Eighty-nine percent of patients had 1 or more NNRTI mutation resistances. Almost all patients had resistance to a...