High rate multiple drug resistances in HIV-infected patients failing nonnucleoside reverse transcriptase inhibitor regimens in Thailand, where subtype A/E is predominant

High rate multiple drug resistances in HIV-infected patients failing nonnucleoside reverse transcriptase inhibitor regimens in Thailand, where subtype A/E is predominant

The prevalence of drug resistance was determined among 64 HIV-infected Thai patients who were failed while receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Eighty-nine percent of patients had 1 or more NNRTI mutation resistances. Almost all patients had resistance to a...

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Bibliographic Details
Main Authors: Ploenchan Chetchotisakd, Siriluck Anunnatsiri, Sasisopin Kiertiburanakul, Ruengpung Sutthent, Thanomsak Anekthananon, Chureeratana Bowonwatanuwong, Boonchai Kowadisaiburana, Khuanchai Supparatpinyo, Manassinee Horsakulthai, Sanchai Chasombat, Kiat Ruxrungtham
Format: Journal
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=35448999929&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/61708
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Institution: Chiang Mai University
Description
Summary:The prevalence of drug resistance was determined among 64 HIV-infected Thai patients who were failed while receiving nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Eighty-nine percent of patients had 1 or more NNRTI mutation resistances. Almost all patients had resistance to at least 1 nucleoside reverse transcriptase inhibitor (NRTI), and 42% had multiple-NRTI resistance. © 2006 Sage Publications.

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