Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR

The Xanthomonas campestris transcription regulator OhrR contains a reactive cysteine residue (C22) that upon oxidation by organic hydroperoxides (OHPs) forms an intersubunit disulphide bond with residue C127′. Such modification induces the expression of a peroxidase that reduces OHPs to their less t...

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Bibliographic Details
Main Authors: Kate J. Newberry, Mayuree Fuangthong, Warunya Panmanee, Skorn Mongkolsuk, Richard G. Brennan
Other Authors: University of Texas MD Anderson Cancer Center
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24080
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Institution: Mahidol University