Structural Mechanism of Organic Hydroperoxide Induction of the Transcription Regulator OhrR
The Xanthomonas campestris transcription regulator OhrR contains a reactive cysteine residue (C22) that upon oxidation by organic hydroperoxides (OHPs) forms an intersubunit disulphide bond with residue C127′. Such modification induces the expression of a peroxidase that reduces OHPs to their less t...
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Main Authors: | Kate J. Newberry, Mayuree Fuangthong, Warunya Panmanee, Skorn Mongkolsuk, Richard G. Brennan |
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Other Authors: | University of Texas MD Anderson Cancer Center |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/24080 |
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Institution: | Mahidol University |
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